[1825 days] Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction
[1825 days] Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction [1825 days] Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction

[1825 days] Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction

0 đánh giá

CHI TIẾT SẢN PHẨM

Mã sản phẩm:
9780444508355
Tồn kho:
Còn hàng
Danh mục
Mua eTextbooks trực tuyến
Nhà xuất bản:
Elsevier S & T
Loại bìa:
Page Fidelity
Ngôn ngữ:
English
Tác giả:
Kaczmarek, L.; Robertson, H.A.


Special Price 9,271,000 VNĐ

Còn VNĐ nữa bạn sẽ được miễn phí giao hàngTìm hiểu thêm

Mua hàng số lượng lớn

Thời gian giao hàng Xem thêm

Chính sách đổi trả Xem thêm

Số lượng

That molecular neurobiology has become a dominant part of neuroscience research can be credited to the discovery of inducible gene expression in the brain and spinal cord. This volume deals with genes, whose expression patterns in the vertebrate central nervous system were the first to be revealed and then the most extensively investigated over the last 15 years. Immediate early genes (IEG) and their protein products, especially those acting as regulators of transcription (inducible transcription factors, ITF) have proven to be very valuable tools in functional neuroanatomy and neurophysiology, as they are rapidly and transiently induced in specific neurons in response to various modes of stimulation. Thus, they have been used to map neuronal populations selectively responsive to a variety of conditions, such as sensory and learning experience, electrical stimulation of specific circuits, seizures, and neurodegeneration.


This single volume, written by the most prominent authors in the field, brings together for the first time information about the most widely studied IEG/ITF in a whole variety of phenomena of neuronal activation. It starts with a critical appraisal of the technologies employed for the studies on gene, protein, and transcription factor activity in the nervous system. Several chapters present exhaustive examples of expression patterns of the ITF in "vocal" avian brain, mammalian brain sensory regions, areas involved in regulation of circadian rhythms, and the spinal cord. The next parts cover functional and regular aspects of individual IEG/ITF expression: c-fos in learning and memory, c-jun and others in neuropathology and neuronal stress responses, Elk-1, egr family, and CREB in neuronal plasticity and learning.

This volume will be useful as a major reference on this topic. Furthermore, it attempts to unravel the seemingly overwhelming complexity of the phenomena of gene expression in the central nervous system.

Sản phẩm liên quan

New
[1825 days] Kassel v. Consolidated Freightways Corporation of Delaware, 450 U.S. 662
[1825 days] Kassel v. Consolidated Freightways Corporation of Delaware, 450 U.S. 662

This title is from the Hayes Barton Press "Originals" series, a collection of classic fiction and no..

38,000 VNĐ

New
[1825 days] The Psychoanalytic Study of Lives Over Time: Clinical and Research Perspectives on Children Who Return to Treatment in Adulthood
[1825 days] The Psychoanalytic Study of Lives Over Time: Clinical and Research Perspectives on Children Who Return to Treatment in Adulthood

The Psychoanalytic Study of Lives Over Time: Clinical and Research Perspectives on Children Who Retu..

1,904,000 VNĐ

New
[1825 days] The Histories of Herodotus: Book VII, Polymnia
[1825 days] The Histories of Herodotus: Book VII, Polymnia

This title is from the Hayes Barton Press "Originals" series, a collection of classic fiction and no..

38,000 VNĐ

New
[1825 days] Advances in Inorganic Chemistry
[1825 days] Advances in Inorganic Chemistry

Advances in Inorganic Chemistry presents timely and informative summaries of the current progress in..

6,985,000 VNĐ

New
[1825 days] Advances in Organometallic Chemistry
[1825 days] Advances in Organometallic Chemistry

This widely acclaimed serial contains authoritative reviews that address all aspects of organometall..

5,486,500 VNĐ

New
[1825 days] A Guide to Ship Repair Estimates in Man Hours
[1825 days] A Guide to Ship Repair Estimates in Man Hours

Don Butler has compiled an invaluable list of the man-hours required for ship repair estimates. All ..

1,878,500 VNĐ

New
[1825 days] ADVANCES IN PHARMACOLOGY VOL 23
[1825 days] ADVANCES IN PHARMACOLOGY VOL 23

ADVANCES IN PHARMACOLOGY VOL 23..

1,853,000 VNĐ

New
[1825 days] Of Agriculture
[1825 days] Of Agriculture

Cowley's essays are written with great simplicity and naturalness, and exhibit his temperament in a ..

38,000 VNĐ

0898536989
Trang chủ
Tài khoản
0
Giỏ hàng
Thanh toán