[1825 days] Serotonin Receptors and their Ligands
[1825 days] Serotonin Receptors and their Ligands [1825 days] Serotonin Receptors and their Ligands

[1825 days] Serotonin Receptors and their Ligands

0 đánh giá

CHI TIẾT SẢN PHẨM

Mã sản phẩm:
9780444820419
Tồn kho:
Còn hàng
Danh mục
Mua eTextbooks trực tuyến
Nhà xuất bản:
Elsevier S & T
Loại bìa:
Page Fidelity
Ngôn ngữ:
English
Tác giả:
Olivier, B.; van Wijngaarden, I.; Soudijn, W.


Special Price 10,541,000 VNĐ

Còn VNĐ nữa bạn sẽ được miễn phí giao hàngTìm hiểu thêm

Thời gian giao hàng Xem thêm

Chính sách đổi trả Xem thêm

Số lượng

An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds (selectively) acting at serotonin receptors or serotonin transporters either as agonists, partial agonists or antagonists.

Structure - affinity relationships and structure - activity relationships of agonists, partial agonists, and antagonists of 5-HT receptors and uptake sites, are discussed. Structure, sequence homology and the effect of site-directed mutations of 5-HT receptors and the reuptake site on the binding of ligands show the tremendous impact of molecular biology on medicinal chemistry research. Also discussed is the pharmacology and (potential) clinical applications of ligands for the 5-HT receptors and the reuptake site. By developing elegant techniques of cloning and expression of serotonin receptor subtypes, their mutants and chimeras, a unique opportunity was offered to study the binding mode of serotoninergic ligands to their receptors and transporters.

The distribution, structure and homologies of serotonin receptor subtypes and the structure of the serotonin transporter are also taken into account.

The (potential) therapeutic applications of ligands of the different subtypes are described.

Altogether an excellent addition to the Pharmacochemical Library series.

Sản phẩm liên quan

New
[1825 days] The Scarlet Letter
[1825 days] The Scarlet Letter

Three settlers' secrets entangle them in a shameful love triangle during 1640's Puritan New England ..

38,000 VNĐ

New
[1825 days] Communist Party of the United States v. Subversive Activities Control Bd. No. 12, 367 U.S. 1
[1825 days] Communist Party of the United States v. Subversive Activities Control Bd. No. 12, 367 U.S. 1

This title is from the Hayes Barton Press "Originals" series, a collection of classic fiction and no..

38,000 VNĐ

New
[30 days] Development of Achievement Motivation
[30 days] Development of Achievement Motivation

This book discusses research and theory on how motivation changes as children progress through schoo..

1,042,500 VNĐ

New
[180 days] Prejudice: The Target's Perspective
[180 days] Prejudice: The Target's Perspective

This book turns the tables on the way prejudice has been looked at in the past. Almost all of the cu..

1,006,000 VNĐ

New
[1825 days] Tumor Suppressing Viruses, Genes, and Drugs: Innovative Cancer Therapy Approaches
[1825 days] Tumor Suppressing Viruses, Genes, and Drugs: Innovative Cancer Therapy Approaches

Tumor Suppressing Viruses, Genes, and Drugs profiles the new generation of cancer treatments now in ..

3,708,500 VNĐ

New
[1825 days] First Inaugural Address
[1825 days] First Inaugural Address

This title is from the Hayes Barton Press "Originals" series, a collection of classic fiction and no..

38,000 VNĐ

New
[1825 days] Multiple Sclerosis As A Neuronal Disease
[1825 days] Multiple Sclerosis As A Neuronal Disease

This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neur..

6,477,000 VNĐ

New
[1825 days] Deep Challenge: Our Quest for Energy Beneath the Sea: Our Quest for Energy Beneath the Sea
[1825 days] Deep Challenge: Our Quest for Energy Beneath the Sea: Our Quest for Energy Beneath the Sea

Deep Challenge blends oil-patch history, eyewitness accounts of disasters, and open access to the of..

1,599,000 VNĐ

0898536989
Trang chủ
Tài khoản
0
Giỏ hàng
Thanh toán