Pediatric Bone is the first book to be published to deal exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone which are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to the causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in childrenKey Features* Deals exclusively with bone development and diseases of children and each chapter written by an * Fully referenced providing an appendix of usually difficult to find information on the investigation of pediatric bone disease and reference values* Covers both the physiology of bone and mineral homeostasis in children and diseases in one book* Includes a CD-ROM of images..

Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.The last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many of the leading researchers in the field.With genetic studies as a backbone to this volume many chapters are devoted to the function and regulation of amyloid b-protein precursor (APP) and apolipoprotein E (ApoE). Other chapters describe cell biological approaches helping to piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease.Although APP and its proteolytic cleavage product, amyloid b-protein, do not answer all the questions, detailed research into this system has undoubtedly increased our knowledge of the pathobiology of AD and has lead to the identification of other risk factors. Understanding the role of ApoE in the pathology of Alzheimer's disease promises to open a whole new field in AD research.* * Reviews the current knowledge of the pathogenesis of Alzheimer's Disease from a clinical perspective to a genetic and cell biological perspective* A comprehensive description of the role of amyloid B-protein precursor in Alzheimer's disease.* Up-to-date research data* Clear illustrations complement the text..

People working in development of drugs, pesticides, washing detergents, etc., are obliged by law to conduct analyses of the "metabolic pathways" or "maps" for the chemical compounds that they are using or proposing. Everyone in these industries or carrying out research toward such products is therefore interested in having a reference on these compounds.Key Features* Covers literature relating to degradation and metabolic profiles of molecules* Draws together the literature on degradation and metabolism patterns with that on diversified conditions of the environmental systems* Indicates 3D chemical structures, predicted physico-chemical parameters, logP and the SMILES chemical notations of the parent compounds to assist scientists design the lead compounds for new discovery using computer-aided technology..

The Industrial Ventilation Design Guidebook addresses the design of air technology systems for the control of contaminants in industrial workplaces such as factories and manufacturing plants. It covers the basic theories and science behind the technical solutions for industrial air technology and includes publication of new fundamental research and design equations contributed by more than 40 engineers and scientists from over 18 countries.Readers are presented with scientific research and data for improving the indoor air quality in the workplace and reducing emissions to the outside environment.The Guidebook represents, for the first time, a single source of all current scientific information available on the subject of industrial ventilation and the more general area of industrial air technology. New Russian data is included that fills several gaps in the scientific literature.* Presents technology for energy optimization and environmental benefits* A collaborated effort from more than 60 ventilation experts throughout 18 countries* Based on more than 50 million dollars of research and development focused on industrial ventilation* Includes significant scientific contributions from leading ventilation experts in Russia* Presents new innovations including a rigorous design methodology and target levels* Contains extensive sections on design with modeling techniques* Content is well organized and easily adaptable to computer applications..

Basic Medical Endocrinology, Third Edition provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. The discussion focuses on molecular and cellular aspects of hormone production and action firmly rooted in the context of integrative physiology. Topics are approached from the perspective of a physiologist with four decades of teaching experience. This book is richly illustrated with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. Each of the thirteen in-depth chapters starts with an 'Overview' of the topic and ends with a 'Suggested Reading' list.* Single authorship provides continuity and consistency between chapters * Richly illustrated with over 200 illustrations* IThirteen in-depth chapters incorporating the latest insights gleaned from rapidly expanding genetic studies of humans and rodents* Author has taught subject for over 40 years..

Assessment and Culture challenges the classical approach to the assessment of minority populations by pointing out the deficiencies in this approach and offers instead a bio-cultural model of assessment. The principle objective of this book is to help mental health professionals to more accurately assess individuals from various ethnic, cultural and linguistic backgrounds. The culture-fair techniques and strategies of the book tap into a broad range of the abilities and aptitudes of the examinee. Assessment and Culture provides a cultural frame of reference which allows the examiner to take into account the individual's social and cultural factors in development, coping style and personal history. Individual chapters consider the practical aspects of assessing the intellectual, linguistic, academic, visual-motor, emotional and vocational functioning of culturally diverse children. An entire section of the book is devoted to writing the assessment report...

Anomia is the inability to access spoken names for objects, most often associated with the elderly or those with brain damage to the left hemisphere. Anomia offers the state-of-the-art review of disorders of naming, written by acknowledged experts from around the world, approached from both clinical and theoretical viewpoints. Goodglass, known around the world for his research in aphasia and speech pathology, edits this first book devoted exclusively to naming and its disorders. Wingfield is known for his classic studies of lexical processing in aphasic and normal speakers. The book includes comprehensive literature reviews, a summary of relevant research data, as well as astudy of recent advances in cognitive analysis and anatomic findings. Anomia is an immensely useful work for all those involved in the study of language, particularly those in cognitive neuroscience, neurology, speech pathology, and linguistics.Key Features* Devoted entirely to naming and its disorders* Includes up-to-date descriptions of advances in cognitive analysis* Contains approaches from both clinical and theoretical viewpoints* Brings together the top researchers from the U.S., England, and Italy..

This broad text provides a complete overview of most standard statistical methods, including multiple regression, analysis of variance, experimental design, and sampling techniques. Assuming a background of only two years of high school algebra, this book teaches intelligent data analysis and covers the principles of good data collection.* Provides a complete discussion of analysis of data including estimation, diagnostics, and remedial actions* Examples contain graphical illustration for ease of interpretation * Intended for use with almost any statistical software* Examples are worked to a logical conclusion, including interpretation of results* A complete Instructor's Manual is available to adopters..

The new level of precision and global coverage provided by satellite altimetry is rapidly advancing studies of ocean circulation. It allows for new insights into marine geodesy, ice sheet movements, plate tectonics, and for the first time provides high-resolution bathymetry for previously unmapped regions of our watery planet and crucial information on the large-scale ocean features on intra-season to interannual time scales. Satellite Altimetry and Earth Sciences has integrated the expertise of the leading international researchers to demonstrate the techniques, missions, and accuracy of satellite altimetry, including altimeter measurements, orbit determination, and ocean circulation models.Satellite altimetry is helping to advance studies of ocean circulation, tides, sea level, surface waves and allowing new insights into marine geodesy. Satellite Altimetry and Earth Sciences provides high resolution bathymetry for previously unmapped regions of our watery planet.Satellite Altimetry and Earth Sciences is for a very broad spectrum of academics, graduate students, and researchers in geophysics, oceanography, and the space and earth sciences. International agencies that fund satellite-based research will also appreciate the handy reference on the applications of satellite altimetry...

The book provides both the theoretical and the applied background needed to predict magnetic fields. The theoretical presentation is reinforced with over 60 solved examples of practical engineering applications such as the design of magnetic components like solenoids, which are electromagnetic coils that are moved by electric currents and activate other devices such as circuit breakers. Other design applications would be for permanent magnet structures such as bearings and couplings, which are hardware mechanisms used to fashion a temporary connection between two wires.This book is written for use as a text or reference by researchers, engineers, professors, and students engaged in the research, development, study, and manufacture of permanent magnets and electromechanical devices. It can serve as a primary or supplemental text for upper level courses in electrical engineering on electromagnetic theory, electronic and magnetic materials, and electromagnetic engineering...

The rapid advances and industry demands for networked delivery of information and pictures through computer networks and cable television has created a need for new techniques and standards for the packaging and delivery of digital information. Multimedia Communications presents the latest information from industry and academic experts on all standards, methods and protocols. Internet protocols for wireless communications, transcoding of Internet multimedia for universal access, ATM and ISDN chapters, videoconferencing standards, speech and audio coding standards, multi-casting and image compression techniques are included.* Latest Internet protocols for wireless communications* Transcoding of Internet multimedia for universal access* ATM and ISDN chapters* Videoconferencing standards* Speech and audio coding standards* Multi-casting* Latest image compression techniques..

The Lyapunov and Riccati equations are two of the fundamental equations of control and system theory, having special relevance for system identification, optimization, boundary value problems, power systems, signal processing, and communications. The Lyapunov Matrix Equation in System Stability and Control covers mathematical developments and applications while providing quick and easy references for solutions to engineering and mathematical problems. Examples of real-world systems are given throughout the text in order to demonstrate the effectiveness of the presented methods and algorithms. The book will appeal to practicing engineers, theoreticians, applied mathematicians, and graduate students who seek a comprehensive view of the main results of the Lyapunov matrix equation.Presents techniques for solving and analyzing the algebraic, differential, and difference Lyapunov matrix equations of continuous-time and discrete-time systems Offers summaries and references at the end of each chapter Contains examples of the use of the equation to solve real-world problems Provides quick and easy references for the solutions to engineering and mathematical problems using the Lyapunov equation..

This book is intended to help newly graduated chemists, particularly organic chemists, at all levels from bachelors to post-doctorates, find careers in the North American pharmaceutical industry. It will serve as a practical, detailed guiedbook for job seekers as well a reference work for faculty advisers, research supervisors, development officers, employment agents, and personnel managers in the industry. The book gathers in a single volume the fundamentals of getting an industrial job as a medicinal or process chemist, and covers all aspects of a chemist's job--scientific, financial, and managerial--within a pharmaceutical/biotechnology company. Other scientists looking for jobs as analytical or physical chemists and even biochemists and biologists will find the book useful. The valuable appendix is a unique compendium of 365 commercial, governmental, or non-profit institutions that comprise the North American pharmaceutical industry.Key Features* Learn How To:* Discover the 12 permanent, big-pharma jobs for B.S. chemists* Use the 500+ company index to locate potential employers* Track pharma openings with 190+ corporate and chemist-specific job banks* Add industry veterans to your employment network* Find the 50+ companies offering paid summer internships to students* Include the one resume item that wins interviews for B.S. and M.S. chemists* Express a knowledgeable preference for drug discovery or development* Research over 360 drug companies through their Web sites* Discover the 70+ firms offering stock purchase plans or stock options¾and which two represent big pharma* Find out your salary offer in time to negotiate your wages..

Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramatic advances in our understanding of the mechanisms of immunity.The field has attracted a continuous stream of the brightest theoretical and experimental scientists for over forty years. This book conveys the philosophies and approaches of sixteen of the most successful of these scientists in the form of a series of narratives that describe the circumstances that led to a major discovery in immunology. Contributors not only recall an exciting period of research that helped shape modern immunology, but set it in the personal context of place and time. Jacques Miller, for example, describes the discovery of the function of the thymus, Rolf Zinkernagel explains how experiments on viral immunity led to the discovery of MHC restriction and Susumu Tonegawa provides an account of how antibody gene structure was defined. Medically-important discoveries include descriptions of early studies of autoimmunity by Noel Rose and of tumour immunology by George and Eva Klein.Far from being a collection of disinterested, historical accounts, this volume comprises a series of passionately biographical, personal essays that provide an unusually intimate insight into the scientific process. This book will be essential, and fascinating, reading for all those with an interest in immunology, and in the life sciences in general. For students and teachers, this will provide the background necessary for a true understanding of immunology, and to place subsequent discoveries in perspective...

For centuries, scholars have debated the causes of aggression and the means to reduce its occurrence. Human Aggression brings together internationally recognized experts discussing the most current psychological research on the causes and prevention of aggression. Scholars, policy makers, practitioners, and those generally concerned with the growing issue of aggression find this a much needed reference work. Topics include how aggression is related to the usage of drugs, how temperature affects aggression, the effect of the mass media on aggression, violence by men against women, and the treatment of anger/aggression in clinical settings. The book also provides a comprehensive review of theory and methodology in the study of aggression.Key Features* Presents the latest research findings from internationally recognized researchers* Familiarizes the reader with implications of aggression research* Examines the causes and prevention of aggression* Offers perspectives for both the researcher and policy maker..

Assessment and Therapy is a derivative volume of articles pulled from the award-winning Encyclopedia of Mental Health, presenting a comprehensive overview of assessing and treating the many disorders afflicting mental health patients, including alcohol problems, Alzheimer's disease, depression, epilepsy, gambling, obsessive-compulsive disorder, phobias, and suicideAccording to 1990 estimates, mental disorders represent five of the ten leading causes of disability.* Among "developed" nations, including the United States, major depression is the leading cause of disability. Also near the top of these rankings are bipolar depression, alcohol dependence, schizophrenia, and obsessive-compulsive disorder. In addition, mental disorders are tragic contributors to mortality, with suicide perennially representing one of the leading preventable causes of death worldwide.Assessment and Therapy describes the impact of mental health on the individual and society and illustrates the factors that aid positive mental health. Twenty-six peer-reviewed articles written by more than 40 expert authors include essential material on assessing and treating schizophrenia, manic-depressive illness, major depression, anxiety disorders, and other mental illnesses. Professionals and libraries will find this timely work indispensable...