[1825 days] Glutamate
[1825 days] Glutamate [1825 days] Glutamate

[1825 days] Glutamate

CHI TIẾT SẢN PHẨM

Mã sản phẩm:
9780444502865
Tồn kho:
Còn hàng
Nhà xuất bản:
Loại bìa:
Page Fidelity
Ngôn ngữ:
English
Tác giả:
Storm-Mathisen, J.; Ottersen, O.P.


Special Price 6,604,000 VNĐ

Còn VNĐ nữa bạn sẽ được miễn phí giao hàngTìm hiểu thêm

Thời gian giao hàng Xem thêm

Chính sách đổi trả Xem thêm

Số lượng

The volume presents a comprehensive and up-to-date treatise of the glutamatergic synapse and its environment. Particular emphasis is on the localizations of the molecular constituents of the synaptic machinery. Immunogold and other high-resolution methods are used extensively. Each chapter presents new data that have not previously been reviewed. The material presented forms the basis for work directed to understanding the functional properties of excitatory synapses in greater depth, to discover mechanisms of neurological and psychiatric disorders and novel methods for treatment.
Chapter 1 deals with the transmitter molecule itself, mechanisms of release and pathways for glutamate synthesis. The anatomy of glutamatergic nerve projection pathways in different brain regions is dealt with. In Chapter 2, focus is on aspartate, the enigmatic congener of glutamate, and its possible role in excitatory neurotransmission. Chapters 3 through 6 deal with glutamate receptors. Metabotropic glutamate receptors are presented in Chapter 3. Chapter 4 presents an in situ hybridization atlas of the different classes of ionotropic glutamate receptors. The localizations of these receptors at the regional and synaptic level are presented in Chapter 5. The ways in which the receptors are brought to the synapse and held in position are the subject of Chapter 6. Chapter 7 deals with the enzymes responsible for formation and catabolism of glutamate. In Chapter 8, the regulation of extracellular glutamate levels by glutamate transporters is discussed. The final two chapters of the volume focus on two "model synapses" that, due to special features, lend themselves particularly well to demonstrating properties of glutamatergic synapses. The hair cell-to-afferent nerve terminal synapses in the inner ear (Chapter 9), with their supporting cells, share essential properties with glutamatergic synapses in the central nervous system. The salient features of the latter are illustrated by the synapses of the giant reticulo-spinal axons of the lamprey, used to unravel molecular mechanisms of the cycling of synaptic vesicles (Chapter 10).

Sản phẩm liên quan

New
[1825 days] Appeal of Forty Thousand Citizens, Threatened with Disfranchisement, to the People of Pennsylvania

This title is from the Hayes Barton Press "Originals" series, a collection of classic fiction and no..

38,000 VNĐ

New
[1825 days] Advances in Physical Organic Chemistry

Advances in Physical Organic Chemistry..

1,853,000 VNĐ

New
[1825 days] ADV EXPERIMENTAL SOCIAL PSYCHOLOGY,V 10

ADV EXPERIMENTAL SOCIAL PSYCHOLOGY,V 10..

1,853,000 VNĐ

New
[1825 days] Mathematical Thinking and Writing: A Transition to Higher Mathematics

The ability to construct proofs is one of the most challenging aspects of the world of mathematics. ..

2,718,000 VNĐ

New
[1825 days] Applications of Chimeric Genes and Hybrid Proteins, Part A: Gene Expression and Protein Purification: Gene Expression and Protein Purification

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one..

5,334,000 VNĐ

New
[1825 days] An Introduction to Predictive Maintenance

This second edition of An Introduction to Predictive Maintenance helps plant, process, maintenance a..

2,870,500 VNĐ

New
[150 days] Identification of Pathological Conditions in Human Skeletal Remains

Identification of Pathological Conditions in Human Skeletal Remains provides an integrated and compr..

1,867,000 VNĐ

New
[1825 days] Avian Embryology

This revised edition will continue to serve as the most complete and up-to-date guide to the use of ..

4,318,000 VNĐ

0898536989