[1825 days] T Cell Subsets: Cellular Selection, Commitment and Identity

[1825 days] T Cell Subsets: Cellular Selection, Commitment and Identity

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CHI TIẾT SẢN PHẨM

Mã sản phẩm:

9780120224838

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Nhà xuất bản:

Elsevier S & T

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Ngôn ngữ:

English

Tác giả:

Alt, Frederick W.

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This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.

T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers

[1825 days] T Cell Subsets: Cellular Selection, Commitment and Identity

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