This volume of Advances in Protein Chemistry provides a broad, yet deep look at the cellular components that assist protein folding in the cell. This area of research is relatively new--10 years ago these components were barely recognized, so this book is a particularly timely compilation of current information. Topics covered include a review of the structure and mechanism of the major chaperone components, prion formation in yeast, and the use of microarrays in studying stress response. Outlines preceding each chapter allow the reader to quickly access the subjects of greatest interest. The information presented in this book should appeal to biochemists, cell biologists, and structural biologists...

Hot Spot Pollutants describes how pharmaceuticals and/or endocrine active compounds gain entry into the aquatic ecosystem, effects on specific organisms and the potential risk involved for the whole ecosystem. In addition it presents the latest views and developments regarding legal requirements for assessing the environmental risk of pharmaceuticals. This books includes the views of academic, industry and government scientists, and thus aims for a balanced presentation of all standpoints. The book consists of papers that appeared previously in the journal Toxicology Letters in 2002 and 2003, and have been collected in this single volume to make them accessible to a broader audience. Authors were asked to update their contributions where necessary. See also Toxicology Letters volume 131, issues 1 and 2 (2002), and volume 142 issue 3 (2003).* State-of-the-art information of pharmaceuticals in the environment* Leading Academic, industry and government contributors* Provides the views of the experts in the field* Offers a thorough basis to attain a good overview including all facets of the field..

A wide range of researchers are currently investigating different properties and applications for copper-containing proteins. Biochemists researching metal metabolism in organisms ranging from bacteria to plants to animals are working in a completely different area of discovery than scientists studying the transportation and regulation of minerals and small molecule nutrients. They are both working with copper-containing proteins, but in very different ways and with differing anticipated outcomes...

This volume focuses on issues of plant pathology and sustainability, such as short term economic plans versus long term economic visions in farming and forestry. The book also deals with the complex biological interactions governing success in minimizing pest or pathogen damage by biological or chemical strategies, benefits and costs to the producer, consequences for the environment of management options, and the challenge of defining useful farm or forest indicatorsof sustainable practices...

Parasitology continues to benefit from taking an evolutionary approach to its study. Tree construction, character-mapping, tree-based evolutionary interpretation, and other developments in molecular and morphological phylogenetics have had a profound influence and have shed new light on the very nature of host-parasite relations and their coevolution. Life cycle complexity, parasite ecology and the origins and evolution of parasitism itself are all underpinned by an understanding of phylogeny.This volume aims to bring together a range of articles that exemplifies the phylogenetic approach as applied to various disciplines within parasitology and as applied by parasitologists. Unified by the use of phylogenies, this book tackles a wide variety of parasite-specific biological problems across a diverse range of taxa.* Includes important contributions from leading minds in the field such as Serge Morand, Francisco Ayala and Mark Blaxter, among others.* Second in the ISI Parasitology List in 2002 with an Impact Factor of 4.818* Series encompasses over 35 years of parasitology coverage..

The Roles of Vasopressin and Oxytocin in Memory Processing reviews research progress in a subfield of Behavioral Pharmacology concerned with vasopressin’s (VP’s) and oxytocin (OT’s) roles in memory processing (MP). As hormones, VP is well-known for its pressor and antidiuretic action, and OT for its contribution to parturition and nursing. As neurotransmitters, they participate in a wide variety of self- and species-preserving functions expressed at psychological, physiological and behavioral levels. Advances in Pharmacology is available online on ScienceDirect — full-text online of volumes 48 onwards. Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elsevier’s extensive researcher network. For more information about the Elsevier Book Series on ScienceDirect Program, please visit:http://www.info.sciencedirect.com/bookseries/* Comprehensive coverage of both alternative theories and relevant research* Several key chapters reviewed by researchers whose studies and theories formed the subject matter of these chapters* Basic laboratory research focus with potential application for understanding and treating human memory disorders..

Hormones and Signaling focuses on the mechanisms of gene regulation at the cellular level. It also describes the actions of hormones in modulating gene regulation and animal development.Key Features* Glococorticoid and mineralcorticoid signaling* Orphan nuclear receptors* Nuclear receptor coactivators* Cytokines and STAT signaling* Coordination of cAMP signaling events through PKA anchoring* G protein-coupled extracellular Ca2+ (Ca2+0)-sensing receptor (CaR)* Pancreatic islet development* Genetic analysis of androgen receptors in development and disease* Antioprogestin regulable gene switch for induction of gene expression in vivo* Steroid receptor knockout model..

The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.Key Features* Detailed insights into viral packaging, expression, and assembly* Mechanistic understanding of how HIV interacts with receptors and infects cells* Delineation of virally encoded regulatory processes unique to HIV* Clinical Applications:* An updated review of current chemotherapeutics for HIV* New concepts in the discovery and design of novel anti-HIV drugs* The latest developments in HIV-vaccine research..

The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.Key Features* Detailed insights into viral packaging, expression, and assembly* Mechanistic understanding of how HIV interacts with receptors and infects cells* Delineation of virally encoded regulatory processes unique to HIV* Clinical Applications:* An updated review of current chemotherapeutics for HIV* New concepts in the discovery and design of novel anti-HIV drugs* The latest developments in HIV-vaccine research..

Advances in Inorganic Chemistry presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bioinorganic to solid state. This acclaimed serial features reviews written by experts in the area and is an indispensable reference to advanced researchers. Each volume of Advances in Inorganic Chemistry contains an index, and each chapter is fully referenced...

The seventh volume of Advances in Pharmaceutical Sciences heralds a welcome continuation of this well-respected series. Acknowledged experts provide comprehensive statements of current research and development in selected fields of pharmaceutical technology. This book will be of great value to those working in academia and the pharmaceutical industry...

Almost all branches of chemistry and material science now interface with organometallic chemistry-the study of compounds containing carbon-metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambient temperatures to species which are thermally very stable. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964...

Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.. Provides an authoritative, definitive review addressing all aspects of organometallic chemistry.. Useful to all researchers within this active field and is a must for every modern library of chemistry.. High quality research book within this rapidly developing field...

This new volume of Advances in Marine Biology contains reviews on a wide range of important subjects such as: long-term oceanographic and ecological research in the western English Channel; marine biofouling on fish farms and its remediation; interactions between behaviour and physical forcing in the control of horizontal transport of decapod crustacean larvae; comparison of marine copepod outfluxes: nature, rate, fate and role in the carbon and nitrogen cycles. Advances in Marine Biology has been providing in-depth and up-to-date reviews on all aspects of Marine Biology since 1963 -- over 40 years of outstanding coverage! The series is well-known for both its excellence of reviews as well as the strength of its thematic volumes devoted to a particular field in detail, such as 'The Biochemical Ecology of Marine Fishes' and 'Molluscan Radiation'. Radiation'.* Series Encompasses 40 Years of Coverage * Up-to-date Reviews on Wide-Ranging Topics..

This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers..

Advances in Inorganic Chemistry presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bioinorganic to solid state. This acclaimed serial features reviews written by experts in the area and is an indispensable reference to advanced researchers. Each volume of Advances in Inorganic Chemistry contains an index, and each chapter is fully referenced...