This book provides a comprehensive description of the architetural techniques to tackle the soft error problem. It covers the new methodologies for quantitative analysis of soft errors as well as novel, cost-effective architectural techniques to mitigate them. To provide readers with a better grasp of the broader problem deffinition and solution space, this book also delves into the physics of soft errors and reviews current circuit and software mitigation techniques. TABLE OF CONTENTSChapter 1: Introduction Chapter 2: Device- and Circuit-Level Modeling, Measurement, and Mitigation Chapter 3: Architectural Vulnerability Analysis Chapter 4: Advanced Architectural Vulnerability Analysis Chapter 5: Error Coding Techniques Chapter 6: Fault Detection via Redundant Execution Chapter 7: Hardware Error Recovery Chapter 8: Software Detection and Recovery* Helps readers build-in fault tolerance to the billions of microchips produced each year, all of which are subject to soft errors* Shows readers how to quantify their soft error reliability * Provides state-of-the-art techniques to protect against soft errors..

Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence.New chapters on:* strain construction* genome-wide two-hybrid approaches * use of microarrays for transcript analysis* real-time analysis of chromosome behaviour and FRET* synthetic gene array technology and protein arrays * chemical genomics and yeast prions * RNA gene analysis and mitochondrial gene function analysis * phylogenetic footprinting * discovering human gene function and predicting yeast gene function..

Based on the highly successful reference work Viral Pathogenesis published in 1997, this concise, economical version can be used both as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy in a format that is easy to understand without continually referring to additional information. Used by the author in his graduate classes at the University of Pennsylvania, it sets forth the essential principles and discusses the details of how the immune system responds to viral invasion including the treatment and prevention of infection. Illustrated by pertinent examples it is one of the only books devoted exclusively to this topic.* Offers almost a 20% expansion over the first edition * Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic* Neal Nathanson is one of the primary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virology and Topley and Wilson's Microbiology* Now in four color throughout!..

While the highly technical measurement techniques and methodologies of Value at Risk have attracted huge interest, much less attention has been focused on how Value at Risk and the risk-adjusted performance measures such as RAROC or economic profit/EVA„· can be effectively used to improve a bank¡¦s decision making processes. Academic books are typically concerned primarily with measurement techniques, and devote only a small section to describing the applications, usually without discussing the problems that changing organizational processes in banks may have on business units¡¦ behaviour. Practitioners¡¦ books are often based on a single experience, presenting the approach that has been pursued by a single bank, but often do not adequately evaluate that approach. In actual practice, the choice of how to use Value at Risk and risk-adjusted performance measures has no single optimal solution, but requires effective decision making that can identify the solution that is consistent with the bank¡¦s style of management and coordination mechanisms, and often with characteristics of individual business units as well. In this book, Francesco Saita of Bocconi University argues that even though risk measurement techniques have greatly improved in recent years for market, credit and now also operational risk, capital management and capital allocation decisions are far from becoming purely technical and mechanical. On one hand, decisions about capital management must consider handling different capital constraints (e.g. regulatory vs. economic capital ) and face remarkable difficulties in providing a measure of ¡§aggregated¡¨ Value at Risk (i.e. a measure that considers the overall value at risk of the bank after diversification across risk types). On the other hand, the aim of using capital more efficiently through capital allocation cannot be achieved only through a sort of centralized asset allocation process, but rather by designing a Value at Risk limit system and a risk-adjusted performance measurement system that are designed to provide the right incentives to individual business units. This connection between sophisticated and cutting edge risk measurement techniques and practical bank decision making about capital management and capital allocation make this book unique and provide readers with a depth of academic and theoretical expertise combined with practical and real-world understanding of bank structure, organizational constraints, and decisionmaking processes.*Contains concise, expert analysis of the latest technical VaR measures but without the highly mathematical component of other books*Discusses practical applications of these measures in the real world of banking, focusing on effective decision making for capital management and allocation*Author is based at Bocconi University in Milan, Italy, one of the foremost institutions for banking in Europe..

The increasing realization among behaviorists and psychologists is that many animals learn by observation as members of social systems. Such settings contribute to the formation of culture. This book combines the knowledge of two groups of scientists with different backgrounds to establish a working consensus for future research. The book is divided into two major sections, with contributions by a well-known, international, and interdisciplinary team which integrates these growing areas of inquiry.Key Features* Integrates the broad range of scientific approaches being used in the studies of social learning and imitation, and society and culture* Provides an introduction to this field of study as well as a starting point for the more experienced researcher* Chapters are succinct reviews of innovative discoveries and progress made during the past decade* Includes statements of varied theoretical perspectives on controversial topics* Authoritative contributions by an international team of leading researchers..

This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software.* Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA)* Includes a complete list of resources, including relevant online databases and software* Defines technical lingo for novices..

This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine.-Accessible to biologists looking for new ways to model their results and engineers interested in biomedical applications -Useful to researchers in biomaterials, inflammation, and vascular biology -Excellent resource for graduate students as a textbook in cell & tissue engineering or cell mechanics courses..

As the largest living group on earth, insects can provide us with insight into adaptation, evolution, and survival. The 2nd edition of this standard text for insect physiology courses and entomologists provides the most comprehensive analysis of the systems that make insects important contributors to our environment. Physiological Systems in Insects discusses the role of insect molecular biology, nueroendocrinology, biochemistry, and genetics in our understanding of insects. Organized according to insect physiological functions, this book is fully updated with the latest and foundational research that has influenced understanding of the patterns and processes of insects.* Full update of a widely used text for students and researchers in entomology and zoology* Includes recent research that uses molecular techniques to uncover physiological mechanisms* Includes a glossary of physiological terms* New, extended section on locomotive systems* Provides abundant figures derived from scientific reports..

Laboratory Experiments in the Social Sciences is the only book providing core information for researchers about the ways and means to conduct experiments. Its comprehensive regard for laboratory experiments encompasses “how-to” explanations, investigations of philosophies and ethics, explorations of experiments in specific social science disciplines, and summaries of both the history and future of social science laboratories. No other book offers such a direct avenue to enlarging our knowledge in the social sciences.This collection of original chapters combines instructions and advice about the design of laboratory experiments in the social sciences with the array of other issues. While there are books on experimental design and chapters in more general methods books on design, theory, and ethical issues, no other book attempts to discuss the fundamental ideas of the philosophy of science or lays out the methods comprehensively or in such detail. Experimentation has recently prospered because of increasing interest in cross-disciplinary syntheses, and this book of advice, guidelines, and observations underline its potential and increasing importance.· Provides a comprehensive summary of issues in social science experimentation, from ethics to design, management, and financing· Offers "how-to" explanations of the problems and challenges faced by everyone involved in social science experiments· Pays attention to both practical problems and to theoretical and philosophical arguments· Defines commonalities and distinctions within and among experimental situations across the social sciences..

Recently, the 50th anniversary of the publication of Animal Behaviour has passed. To mark the occasion, a group of prominent behaviourists have written essays relevant to their fields. These essays provide a glimpse of the study of behaviour looking in all directions. History and future aside, it is imperative to broadcast this information from the perspective of the behaviourists who have helped shape both the past and the future. It is important for any field to be both retrospective and prospective: where have we been, where are we going, where are we now? These essays provide a unique personal reflection on the history of animal behaviour from John Alcock, Stuart and Jeanne Altmann, Steve Arnold, Geoff Parker, and Felicity Huntingford. Six topics are reflected on and include: The History of Animal Behavioural Research, Proximate Mechanisms, Development, Adaptation, and Animal Welfare.* Broad range of essays on animal behaviour* Written by leaders in the field* Offers a history of the study of behaviour plus essays on the future of behavioural studies* Contains over 30 full color illustrations* Includes essays on development, mechanisms and adaptive significance of behaviour..

Computational Materials Engineering is an advanced introduction to the computer-aided modeling of essential material properties and behavior, including the physical, thermal and chemical parameters, as well as the mathematical tools used to perform simulations. Its emphasis will be on crystalline materials, which includes all metals. The basis of Computational Materials Engineering allows scientists and engineers to create virtual simulations of material behavior and properties, to better understand how a particular material works and performs and then use that knowledge to design improvements for particular material applications. The text displays knowledge of software designers, materials scientists and engineers, and those involved in materials applications like mechanical engineers, civil engineers, electrical engineers, and chemical engineers. Readers from students to practicing engineers to materials research scientists will find in this book a single source of the major elements that make up contemporary computer modeling of materials characteristics and behavior. The reader will gain an understanding of the underlying statistical and analytical tools that are the basis for modeling complex material interactions, including an understanding of computational thermodynamics and molecular kinetics; as well as various modeling systems. Finally, the book will offer the reader a variety of algorithms to use in solving typical modeling problems so that the theory presented herein can be put to real-world use.•Balanced coverage of fundamentals of materials modeling, as well as more advanced aspects of modeling, such as modeling at all scales from the atomic to the molecular to the macro-material•Concise, yet rigorous mathematical coverage of such analytical tools as the Potts type Monte Carlo method, cellular automata, phase field, dislocation dynamics and Finite Element Analysis in statistical and analytical modeling•Companion web site will offer ample workable programs, along with suggested projects, resources for further reading, and useful classroom exercises..

Describes the evidence-based approaches to preventing relapse of major mental and substance-related disorders. Therapist's Guide to Evidence-based Relapse Prevention combines the theoretical rationale, empirical data, and the practical "how-to" for intervention programs.The first section will serve to describe the cognitive-behavioral model of relapse and provide a general introduction to relapse prevention techniques. While Section II will focus on specific problem areas, Section III will focus on diverse populations and treatment settings.*Incorporates theoretical and empirical support*Provides step-by-step strategies for implementing relapse prevention techniques*Includes case studies that describe application of relapse prevention techniques..

Describes the evidence-based approaches to preventing relapse of major mental and substance-related disorders. Therapist's Guide to Evidence-based Relapse Prevention combines the theoretical rationale, empirical data, and the practical "how-to" for intervention programs.The first section will serve to describe the cognitive-behavioral model of relapse and provide a general introduction to relapse prevention techniques. While Section II will focus on specific problem areas, Section III will focus on diverse populations and treatment settings.*Incorporates theoretical and empirical support*Provides step-by-step strategies for implementing relapse prevention techniques*Includes case studies that describe application of relapse prevention techniques..

Describes the evidence-based approaches to preventing relapse of major mental and substance-related disorders. Therapist's Guide to Evidence-based Relapse Prevention combines the theoretical rationale, empirical data, and the practical "how-to" for intervention programs.The first section will serve to describe the cognitive-behavioral model of relapse and provide a general introduction to relapse prevention techniques. While Section II will focus on specific problem areas, Section III will focus on diverse populations and treatment settings.*Incorporates theoretical and empirical support*Provides step-by-step strategies for implementing relapse prevention techniques*Includes case studies that describe application of relapse prevention techniques..

Describes the evidence-based approaches to preventing relapse of major mental and substance-related disorders. Therapist's Guide to Evidence-based Relapse Prevention combines the theoretical rationale, empirical data, and the practical "how-to" for intervention programs.The first section will serve to describe the cognitive-behavioral model of relapse and provide a general introduction to relapse prevention techniques. While Section II will focus on specific problem areas, Section III will focus on diverse populations and treatment settings.*Incorporates theoretical and empirical support*Provides step-by-step strategies for implementing relapse prevention techniques*Includes case studies that describe application of relapse prevention techniques..

Describes the evidence-based approaches to preventing relapse of major mental and substance-related disorders. Therapist's Guide to Evidence-based Relapse Prevention combines the theoretical rationale, empirical data, and the practical "how-to" for intervention programs.The first section will serve to describe the cognitive-behavioral model of relapse and provide a general introduction to relapse prevention techniques. While Section II will focus on specific problem areas, Section III will focus on diverse populations and treatment settings.*Incorporates theoretical and empirical support*Provides step-by-step strategies for implementing relapse prevention techniques*Includes case studies that describe application of relapse prevention techniques..