Describes the evidence-based approaches to preventing relapse of major mental and substance-related disorders. Therapist's Guide to Evidence-based Relapse Prevention combines the theoretical rationale, empirical data, and the practical "how-to" for intervention programs.The first section will serve to describe the cognitive-behavioral model of relapse and provide a general introduction to relapse prevention techniques. While Section II will focus on specific problem areas, Section III will focus on diverse populations and treatment settings.*Incorporates theoretical and empirical support*Provides step-by-step strategies for implementing relapse prevention techniques*Includes case studies that describe application of relapse prevention techniques..

For anyone who treats postmenopausal women, this latest edition of Rogerio Lobo's classic work combines the best from two well-known references: Menopause, and the second edition of Treatment of the Postmenopausal Woman. By adding significant discussions of the basic science behind menopause, it is possible to objectively assess the clinical value and limitations of current approaches to treatment and provide a basis and rationale for strategies that will result in better individualized and specialized care. Not only does the third edition discuss diagnosis and treatment of menopause but it covers biological, anatomical, physiological, pathobiological, and pharmacological aspects as well bringing together, in one source, all of the information needed to understand and treat postmenopausal conditions.* Over 50% new material representing the vast amount of information available since the Women's Health Initiative (WHI) clinical trials were completed making this the most up-to-date reference on postmenopausal women* Includes several new sections on comparisons between clinical trials and observational data, urology, and pelvic support* Each section is preceded by a preface to put the area into context with many chapters having suggested treatment regimens..

The purpose of the book is to bring together in one place the different facets of regenerative biology and medicine while providing the reader with an overview of the basic and clinically-oriented research that is being done. Not only does the content cover a plethora tissues and systems, it also includes information about the developmental plasticity of adult stem cells and the regeneration of appendages.As part of its balanced presentation, Regenerative Biology and Medicine does address the biological/bioethical issues and challanges involved in the new and exciting field of regenerative biology and medicine.*Tissues covered include skin, hair, teeth, cornea, and central neural types*Systems presented are digestive, respiratory, urogenital, musculoskeletal, and cardiovascular*Includes amphibians as powerful research models*Discusses appendage regeneration in amphibians and mammals..

Rabies is the most current and comprehensive account of one of the oldest diseases known that remains a significant public health threat despite the efforts of many who have endeavored to control it in wildlife and domestic animals. During the past five years since publication of the first edition there have been new developments in many areas on the rabies landscape. This edition takes on a more global perspective with many new authors offering fresh outlooks on each topic. Clinical features of rabies in humans and animals are discussed as well as basic science aspects, molecular biology, pathology, and pathogenesis of this disease. Current methods used in defining geographic origins and animal species infected in wildlife are presented, along with diagnostic methods for identifying the strain of virus based on its genomic sequence and antigenic structure. This multidisciplinary account is essential for clinicians as well as public health advisors, epidemiologists, wildlife biologists, and research scientists wanting to know more about the virus and the disease it causes.* Offers a unique global perspective on rabies where dog rabies is responsible for killing more people than yellow fever, dengue fever, or Japanese encephalitis * More than 7 million people are potentially exposed to the virus annually and about 50,000 people, half of them children, die of rabies each year* New edition includes greatly expanded coverage of bat rabies which is now the most prominent source of human rabies in the New World and Western Europe, where dog rabies has been controlled* Recent successes of controlling wildlife rabies with an emphasis on prevention is discussed* Approximately 40% updated material incorporates recent knowledge on new approaches to therapy of human rabies as well as issues involving organ and tissue transplantation* Includes an increase in illustrations to more accurately represent this diseases’ unique horror..

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.* Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology* The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine* New discoveries from leading researchers on restoration of diseased tissues and organs..

This is a much revised and expanded version of the author's previous book Principles of Environmental Science (1988), also published by Elsevier. It incorporates new tools such as ecotechnology, cleaner technology, life cycle analysis and environmental risk assessment, which have changed environmental management strategy radically over the last decade.Sven Jørgensen has worked at the Royal Danish School of Pharmacy as Professor in Environmental Chemistry since 1965, and has also held the position Professor in Environmental Technology at the Danish Agricultural University since 1978. He is Editor in Chief of Ecological Modelling and Editor of the book series Developments in Environmental Modelling...

Physics for Biology and Medicine, Third Edition covers topics in physics as they apply to the life sciences, specifically medicine, physiology, nursing and other applied health fields. This concise introductory paperback surveys and relates basic physics to living systems. It discusses biological systems that can be analyzed quantitatively, and how advances in the life sciences have been aided by the knowledge of physical or engineering analysis techniques. Applicable courses are biophysics and applied physics.- Provides practical techniques for applying knowledge of physics to the study of living systems- Presents material in a straight forward manner requiring very little background in physics or biology- Includes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics..

The rapidly increasing volume of information contained in relational databases places a strain on databases, performance, and maintainability: DBAs are under greater pressure than ever to optimize database structure for system performance and administration. Physical Database Design discusses the concept of how physical structures of databases affect performance, including specific examples, guidelines, and best and worst practices for a variety of DBMSs and configurations. Something as simple as improving the table index design has a profound impact on performance. Every form of relational database, such as Online Transaction Processing (OLTP), Enterprise Resource Management (ERP), Data Mining (DM), or Management Resource Planning (MRP), can be improved using the methods provided in the book.· The first complete treatment on physical database design, written by the authors of the seminal, Database Modeling and Design: Logical Design, 4th edition.· Includes an introduction to the major concepts of physical database design as well as detailed examples, using methodologies and tools most popular for relational databases today: Oracle, DB2 (IBM), and SQL Server (Microsoft).· Focuses on physical database design for exploiting B+tree indexing, clustered indexes, multidimensional clustering (MDC), range partitioning, shared nothing partitioning, shared disk data placement, materialized views, bitmap indexes, automated design tools, and more!..

Proteomics is a systematic approach for studying the identity and function of all proteins expressed in a cell, tissue or organ. New drug targets for diseases are often identified by comparing the proteome of the disease state to the normal state. As a result, proteomics has become increasingly important in the pharmaceutical and biotechnology industries as well as academics. This book contains five sections encompassing the research aspects of proteomics on the brain including the most recent advances in the technology and informatics. It discusses advances in high-throughput proteomic technologies and their application to studying neurological disorders such as Alzheimer’s disease, alcoholism, trauma/stroke, Huntington's disease, and Parkinson's disease. With numerous illustrations to explain the concepts, it provides a comprehensive review on the topic.* Describes the latest databases and techniques for analyzing the data generated by proteomics* Outlines the latest developments in proteomic methods* Provides numerous color illustrations highlighting the application of proteomics to the identification of novel drug targets and biomarkers..

Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds.* Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter * New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more..

Superconductivity, 2E is an encyclopedic treatment of all aspects of the subject, from classic materials to fullerenes. Emphasis is on balanced coverage, with a comprehensive reference list and significant graphicsfrom all areas of the published literature. Widely used theoretical approaches are explained in detail. Topics of special interest include high temperature superconductors, spectroscopy, critical states, transport properties, and tunneling.This book covers the whole field of superconductivity from both the theoretical and the experimental point of view.- Comprehensive coverage of the field of superconductivity- Very up-to date on magnetic properties, fluxons, anisotropies, etc.- Over 2500 references to the literature - Long lists of data on the various types of superconductors..

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.Key Features*Provides solid scientific basis to our understanding of the associations between the brain and the immune system the importance of these connections* Presents coherent development from cellular and molecular neuroimmune communication to social and health considerations, including psychological intervention* Addresses the theory that there is a neurobiology of the immune system..

Mitochondria are critical to the survival of cells, therefore, it is not surprising that abnormalities in mitochondrial function may lead to human disease. This book concentrates on the biology and pathology of mitochondria, covering some ot the important basic science features of the biology of mitochondria. It then moves on to discuss the breadth of human diseases related to mitochondrial dysfunction, including Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Alzheimer's disease.* Provides comprehensive coverage of basic science and clinical features of mitochondrial dysfunction* Presents detailed analysis of "hot" topics in mitochondrial function and neurodegenerative diseases* Includes outstanding list of contributing authors..

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research...

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of articles covering recent advances in the field of neurobiology. Topics covered include behavioral mechanisms and the neurobiology of conditioned sexual responding; NMDA receptors in alcoholism; processing and representation of species-specific communication calls in the auditory system of bats; central nervous system control of micturition; the structure and physiology of the rat auditory system; and neurobiology of cat and human sexual behavior...

International Review of Neurobiology is a well-respected series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a cumulative subject index of volumes 26-50...